Mousse rectale d'hydrocortisone
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 17 Apr 2025
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Note de l'auteur clinique Michael Stewart 17/05/2022: Colifoam® rectal foam was discontinued in the UK in November 2019. At the time of review there are no branded or generic products for rectal use containing hydrocortisone available in the UK. Hydrocortisone rectal foam may still be available in other countries. This medicine leaflet is based on medical information accessed in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Hydrocortisone belongs to a class of medicines known as corticosteroids (more commonly called steroids). It reduces inflammation.
You will have been prescribed it to settle symptoms of flare-up inflammation in the lower parts of your bowel.
The leaflet that comes inside your pack will give you full step-by-step instructions for using the foam. Please read it carefully.
En un coup d'œil
Hydrocortisone rectal foam is a medicine used to reduce inflammation in the rectum and lower colon.
It is often prescribed for flare-ups of ulcerative colitis in the lower bowel.
You apply the foam into your back passage using an applicator.
Treatment usually lasts a few weeks until your flare-up settles.
Inform your doctor about your detailed medical history before using this foam.
Contact your doctor if you become ill or are exposed to chickenpox, measles, or shingles.
Local irritation is an uncommon side-effect, but seek medical advice for changes in behaviour or mood.
About hydrocortisone rectal foam
Type de médicament | A corticosteroid, also commonly called a steroid |
Utilisé pour | Inflammation of the rectum and lower colon |
Aussi appelé | Colifoam® (discontinued) |
Disponible sous forme de | Foam-filled canister with a plastic applicator |
Colite ulcéreuse (UC) is a condition where patches of inflammation develop in your large intestine. The most common symptoms when the disease flares up are diarrhoea mixed with blood, and tummy (abdominal) pain. In between these flare-ups you may have few or no symptoms. If the patches are confined to the lower parts of your bowel (the lower colon and rectum), it may be helpful during flare-ups for you to be treated with a rectal preparation. This means administering hydrocortisone into your back passage as a foam.
Hydrocortisone helps to reduce inflammation. A course of treatment will last a few weeks only - it will be stopped once your flare-up has settled.
Before using hydrocortisone
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start using hydrocortisone it is important that your doctor knows:
If you are pregnant or breastfeeding (even though hydrocortisone could still be prescribed for you).
If you think there may be any blockage in your bowel, or if there are any sore or bleeding areas of skin around your back passage.
Si vous avez une quelconque infection, ou si vous avez déjà eu la tuberculose (TB).
If you have had a heart attack, or if you have a heart condition.
Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.
If you have diabetes (diabetes mellitus), or if you have an eye condition called glaucoma. You should also tell your doctor if a close member of your family has either of these conditions.
If you currently have any of the following conditions: high blood pressure, 'thinning' of the bones (osteoporosis), diverticulitis, an underactive thyroid, epilepsy, cataracts, or a condition causing severe muscle weakness, called myasthenia gravis.
If you have ever had any of the following: a blood clot in a blood vessel, a stomach ulcer, or a mental health problem such as depression or psychosis.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament, ou si vous avez déjà ressenti des douleurs musculaires après avoir pris un médicament stéroïdien.
How to use hydrocortisone rectal foam
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about hydrocortisone, and will also provide you with a full list of the side-effects which you could experience from using it. It will also give you a step-by-step guide on how to use it.
Your doctor will tell you how often to use hydrocortisone foam. It is usual to administer it once or twice a day for 2-3 weeks, and then for the dose to be reduced to once daily or on alternate days for a short while. This information will be on the label of the pack to remind you.
How to use Colifoam®
Shake the canister well before each use.
Withdraw the plunger on the applicator until it stops at the catch line.
Hold the applicator with the nozzle downwards, and then insert the top of the canister of foam into the nozzle.
Press the canister top gently so that foam fills about a quarter of the applicator. Only a short press is needed to do this. Wait a few seconds for the foam to expand and then press the canister top again. Continue to fill the applicator a little at a time until the foam reaches the 'fill' line.
Stand with one leg raised on a chair (or lie down on your side if you prefer) and gently insert the applicator into your back passage. Push the plunger to empty the applicator.
Take the applicator apart and wash it after each use.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor and clinic. This is so your doctor can check on your progress.
Continue to use the foam for as long as your doctor has told you to. A course of treatment is likely to last a few weeks.
If you forget a dose, don't worry, just remember to administer the next dose when it is due.
Hydrocortisone can suppress your immune system, so it is important if you become ill that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have one of these viruses), you should see your doctor as soon as possible.
Some vaccines may not be suitable for you while you are being treated with hydrocortisone. If you need any immunisations, make sure you mention that you are using a steroid medicine.
If you are having an operation or any medical treatment, tell the person carrying out the treatment that you are using hydrocortisone.
If you buy any medicines, check with a pharmacist that they are safe to take with your prescribed medicines.
Can rectal hydrocortisone cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with hydrocortisone when used rectally, although these are uncommon. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Rectal hydrocortisone side-effects (these affect fewer than 1 in 100 people) | Que puis-je faire si je ressens cela ? |
Local irritation | This should soon ease. If it continues, speak with your doctor |
Changes in behaviour or mood | If you become anxious, confused, or start having worrying thoughts about harming yourself, speak with your doctor as soon as possible |
For more information about the side-effects which are possible when hydrocortisone is used over a long period of time, see the separate condition leaflet called Stéroïdes oraux.
If you experience any other symptoms which you think may be due to hydrocortisone, speak with your doctor or pharmacist for further advice.
How to store hydrocortisone
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Never use more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Why was Colifoam® discontinued?
The article mentions Colifoam® as the brand name for hydrocortisone rectal foam but notes that it has been discontinued. It does not specify the reasons why this particular brand was discontinued. However, hydrocortisone rectal foam, the active medicine, is still available under other names.
How does hydrocortisone rectal foam specifically help with ulcerative colitis?
Ulcerative colitis involves inflammation in the large intestine. Hydrocortisone is a corticosteroid, which means it helps to reduce this inflammation. Administering it directly as a foam into the back passage allows it to act locally on the inflamed areas of the lower colon and rectum, relieving symptoms like diarrhoea mixed with blood and tummy pain during flare-ups.
How long will a typical course of hydrocortisone rectal foam treatment last?
A course of treatment will only last a few weeks. It will be stopped once your flare-up has settled. Your doctor will likely instruct you to use it once or twice a day for 2-3 weeks, and then the dose may be reduced to once daily or on alternate days for a short period.
What should I do if I become anxious or have worrying thoughts while using hydrocortisone rectal foam?
Although uncommon, hydrocortisone can sometimes cause changes in behaviour or mood. If you experience anxiety, confusion, or begin to have upsetting thoughts about harming yourself, it is important to speak with your doctor as soon as possible.
Are there any specific situations where I should avoid using a rectal preparation for ulcerative colitis?
Yes, there are some situations where extra care is needed or it might not be suitable. You should tell your doctor if you think there might be any blockage in your bowel, or if you have any sore or bleeding areas of skin around your back passage. These conditions can make rectal administration complicated or unsuitable.
Lectures complémentaires et références
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Next review due: 17 Apr 2028
17 Apr 2025 | Dernière version

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