Co-amoxiclav pour les infections
Augmentin
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 22 Nov 2023
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Make sure you tell your doctor if you are allergic to penicillin. Co-amoxiclav is a type of penicillin - do not take it if you are allergic to penicillin.
Space your doses out evenly over the day and complete the full course of this antibiotic, even if you feel your infection has cleared up. You can take co-amoxiclav before or after food.
Common side-effects of co-amoxiclav are diarrhoea, feeling sick, being sick, and thrush.
If you have an allergic reaction (such as any swelling around your mouth, any difficulties breathing or a red rash) contact a doctor for advice straightaway.
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About co-amoxiclav
Type de médicament | Pénicilline antibiotique |
Utilisé pour | Infections (in adults and children) |
Également appelé | Augmentin® |
Disponible en | Comprimés, médicaments liquides oraux et injections |
What is co-amoxiclav?
Co-amoxiclav is a type of penicillin given to treat bacterial infections. It is prescribed for sinus infections, urine infections, skin infections, joint infections and some dental infections. It is also given before some surgical operations, to prevent an infection from developing.
Co-amoxiclav contains two ingredients, amoxicillin and clavulanic acid. The first ingredient, amoxicillin, is a penicillin antibiotic which treats infection by killing the bacteria responsible for the infection. Some bacteria are able to produce a chemical which makes amoxicillin less effective. The second ingredient, clavulanic acid, stops this from happening. Clavulanic acid stops the chemical produced by the bacteria from working, and this allows the amoxicillin to kill the bacteria.
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Before taking co-amoxiclav
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking co-amoxiclav it is important that your doctor knows:
If you suspect you may have glandular fever.
If you have an allergic condition, or if you have ever had an allergic reaction to a medicine. This is especially important if you have ever had a bad reaction to any penicillin antibiotic.
If you are pregnant or breastfeeding. Co-amoxiclav is not known to be harmful to babies; however, it is still important that you tell your doctor if you are expecting or breastfeeding a baby.
If you have any problems with the way your liver works, or problems with the way your kidneys work.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
How to take co-amoxiclav
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about co-amoxiclav and will provide you with a full list of the side-effects which you may experience from taking it.
Take co-amoxiclav exactly as your doctor tells you to. It is usually taken three times daily, every eight hours. It is important that you space out the doses evenly during the day. Your doctor or pharmacist will tell you how many tablets (or how much liquid medicine) to take for each dose, and this information will be printed on the label of the pack to remind you. If you have been given liquid medicine for a child, read the directions carefully to make sure you measure out the correct amount of medicine.
Try to drink plenty of water while you are taking co-amoxiclav, to help keep your kidneys working well. You can take your doses before or after food.
Si vous oubliez de prendre une dose, prenez-la dès que vous vous en rendez compte. Essayez de prendre le nombre correct de doses chaque jour, mais ne prenez pas deux doses en même temps pour compenser une dose oubliée.
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Tirer le meilleur parti de votre traitement
If you (or your child) have been prescribed the oral liquid medicine, you may find that it causes some staining of the teeth. This will disappear soon after the course of antibiotics is finished.
Even if you feel your infection has cleared up, keep taking the antibiotic until the course is finished, unless you are told to stop. This is to prevent the infection from coming back. Your doctor will tell you how long your course of treatment will last - this is not usually for longer than 14 days. If you still feel unwell after finishing the course, go back to see your doctor.
Some people develop redness and itching in the mouth or vagina (thrush) after taking a course of antibiotics. If this happens to you, speak with your doctor or pharmacist for advice.
If you are taking the contraceptive 'pill' at the same time as this antibiotic, the effectiveness of the 'pill' can be reduced if you have a bout of being sick (vomiting) or diarrhoea which lasts for more than 24 hours. If this should happen, ask your doctor or pharmacist for advice about what additional contraceptive precautions to use over the next few days. There is no need to use additional precautions for any bouts of sickness or diarrhoea which last for less than 24 hours.
Co-amoxiclav may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this antibiotic.
Side-effects of co-amoxiclav
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with co-amoxiclav.
Vous trouverez une liste complète dans la notice d'information du fabricant fournie avec votre médicament. Les effets indésirables s'atténuent souvent au fur et à mesure que votre organisme s'adapte au nouveau médicament, mais consultez votre médecin ou votre pharmacien si l'un des effets suivants persiste ou devient gênant.
Very common co-amoxiclav side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Diarrhée | Drink plenty of water to replace any lost fluids. If the diarrhoea continues, becomes severe, or contains blood, let your doctor know tout de suite |
Common co-amoxiclav side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Se sentir malade (nausées) ou être malade (vomissements) | You can reduce this by taking your doses at a mealtime |
Redness and itching in the mouth or vagina (thrush) | Speak with your doctor for advice about treatment |
Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more co-amoxiclav and speak with your doctor or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the antibiotic, speak with your doctor or pharmacist for further advice.
How to store co-amoxiclav
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Keep co-amoxiclav liquid medicine in a refrigerator, and do not use it after the expiry date on the bottle. It will have been made up by the pharmacy and it is important you do not store or use it for longer than seven days since the date it was made up.
Store co-amoxiclav tablets in a cool, dry place, away from direct heat and light.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez auprès d'un pharmacien qu'ils peuvent être pris en même temps que vos autres médicaments.
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
MHRA - Déclaration des effets indésirables
Signaler à la Medicines and Healthcare products Regulatory Agency les effets secondaires suspectés des médicaments, des vaccins, des e-cigarettes, les incidents liés aux dispositifs médicaux, les produits défectueux ou falsifiés (faux), afin de garantir une utilisation sûre et efficace.
Autres lectures et références
- Manufacturer's PIL, Augmentin® 375 mg tablets; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated July 2022.
- Manufacturer's PIL, Augmentin® 125/31 SF Suspension; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated July 2022.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 21 Nov 2026
22 Nov 2023 | Dernière version

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