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Arthrite septique

L'arthrite septique est une infection d'une articulation. Les symptômes incluent douleur et sensibilité au niveau d'une articulation, douleur lors du mouvement de l'articulation, et sensation de malaise. C'est une infection rare mais grave. Un traitement urgent est nécessaire. Cela inclut des antibiotiques et le drainage du liquide infecté de l'articulation pour prévenir des dommages permanents à l'articulation.

En un coup d'œil

  • L'arthrite septique est une infection articulaire grave causée par des germes, le plus souvent des bactéries.

  • Les symptômes incluent généralement une douleur articulaire sévère et d'apparition rapide, un gonflement, une rougeur et de la fièvre.

  • L'infection peut pénétrer dans une articulation par la circulation sanguine, une blessure ou lors d'une intervention chirurgicale.

  • Les facteurs de risque incluent l'arthrite existante, les blessures articulaires, les articulations artificielles et un système immunitaire affaibli.

  • Le diagnostic implique des analyses de sang et la prise d'un échantillon de liquide directement de l'articulation affectée.

  • Le traitement nécessite des antibiotiques, le drainage du liquide articulaire, et souvent de la physiothérapie.

  • Un traitement rapide est crucial pour prévenir les dommages permanents aux articulations.

Qu'est-ce que l'arthrite septique ?

Many different types of germs (bacteria) can cause septic arthritis. Bacterial infection with Staphylococcus aureus is the most common cause. This bacterium is present on the skin normally and can cause skin infections such as boils and abscesses.

Symptômes de l'arthrite septique

  • Douleur from the affected joint. The pain tends to be severe and develops quite quickly. Any movement of the joint can be very painful.

  • Gonflement usually develops over the affected joint which is usually very tender.

  • Redness of the overlying skin is typical if the joint is near to the skin surface.

  • Feeling generally unwell with a high temperature (fever) is common.

In most cases of septic arthritis the symptoms develop quickly, within a few days. However, with an infection in an artificial joint, the symptoms may not be so dramatic. Pain and fever may be mild at first before gradually becoming worse. Also, in cases caused by the tuberculosis (TB) germ (bacterium), the symptoms may develop more slowly.

Septic arthritis causes

If some germs (bacteria) settle on a small section of a joint, they can multiply and cause infection.

Bacteria can get to a joint:

  • Through the bloodstream. This is the most common cause, particularly in children. Bacteria may get into the blood from an infection in another part of the body and travel to a bone. Even if you are healthy, bacteria from the nose or gut sometimes get into the blood.

  • From an injury. Bacteria can get into a joint if you have a wound that cuts into a joint.

  • During surgery. Infection is an uncommon complication if you have joint surgery or joint investigations (such as arthroscopy).

Septic arthritis risk factors

Septic arthritis is more common in children than in adults, especially in children between ages 2 and 3 years. However, anyone can develop septic arthritis. You have an increased risk if you:

  • Arthritis: if you have certain types of arthritis such as arthrite rhumatoïde. If the joints are already inflamed, they are at greater risk of becoming infected. It can be difficult to tell the difference between a flare-up of non-infective arthritis and infective (septic) arthritis. As a rule, if you already have arthritis and symptoms suddenly become worse and you feel unwell, septic arthritis is a possibility. Tests can confirm, or rule out, an infection.

  • Injury: if you have recently had an injury to a joint.

  • Joint prosthesis: if you have a replacement joint such as an artificial hip or knee.

  • Surgery; if you have recently had surgery to a joint.

  • Weakened immune system; if you have a poor immune system. For example, if you have AIDS, if you are taking chemotherapy, if you are seriously ill with another disease, etc.

  • Drugs; if you inject street drugs which can be contaminated with germs (bacteria).

  • Gonorrhoea; if you have gonorrhoea - a sexually transmitted infection. If untreated, the gonococcus bacteria can spread in the bloodstream and may cause a septic arthritis.

  • Infection of bone; if you have osteomyelitis near to a joint.

Which joints can be affected by septic arthritis?

  • The knee is the site of infection in more than half of cases.

  • The hip is affected in about 1 in 5 cases.

  • The rest are usually the shoulder, wrist, elbow and ankle.

  • Other joints are rarely affected.

In most cases, just one joint is affected. However, in about 1 in 5 cases the germs (bacteria) from one joint spread in the blood to another and two or more joints may be affected at the same time.

Des tests sont-ils nécessaires ?

Tests to confirm the diagnosis of septic arthritis

If you have typical symptoms coming from a joint near to the skin surface then the diagnosis may be fairly clear from the history and physical exam. However, pain coming from deeper joints such as the hip may be due to a number of causes.

  • Certain analyses de sang can help to confirm that you have severe inflammation 'somewhere' in the body, which may be septic arthritis.

  • A plain X-ray is not so useful to diagnose the early stages of septic arthritis. However, it may be a useful test to rule out other causes of joint pain.

  • Une échographie, scanner CT ou IRM of the joint may help to confirm the diagnosis.

Tests pour identifier quel germe (bactérie) cause l'infection

The blood often contains some bacteria from the infected joint.

  • Samples of blood are sent to the laboratory to identify which type of bacterium is causing the infection. This is important, as it will help to decide which is the best treatment. (Some bacteria are resistant to some antibiotic medicines.)

  • Sample of fluid from the joint. If septic arthritis is suspected, a sample of fluid from the joint (the synovial fluid) is also taken by a fine needle. Tests on the fluid can usually confirm the diagnosis and identify the bacterium which is causing the infection.

Septic arthritis treatment

Médicaments antibiotiques

Antibiotics are started as soon as possible. At first, high doses are given straight into a vein. The antibiotics chosen are ones that are likely to kill the germs (bacteria) which commonly cause septic arthritis. However, the antibiotics are sometimes changed to different ones when the results of the tests confirm which bacterium is causing the infection. (Some bacteria are resistant to some antibiotics.) The symptoms often settle quite quickly after starting antibiotics. However, you need to continue taking the antibiotics for several weeks. This is to make sure all infection has gone from the joint.

Draining the joint fluid

Infected fluid is drained from the affected joint. This helps to stop damage to the joint while the antibiotics clear the infection. With an infection in a knee, elbow or shoulder joint the drainage may be relatively easy to do with a needle. However, deeper joints such as a hip joint are more difficult and may need a small operation to drain the infected fluid. The joint may need to be drained several times until infected fluid stops building up.

Attelle

The affected joint may need to be splinted, as movement can be very painful at first.

Physiothérapie

Once the infection has been treated and when symptoms begin to settle it is important to get the affected joint moving again. This may help to prevent long-term stiffness in the affected joint.

If the infection is in an artificial joint

The most common artificial joints to become infected are elbow, shoulder and ankle joints, followed by knee and hip joints. The joint often has to be removed to treat the infection properly. However, in many cases a new joint can be inserted with a good chance of success.

Quel est le pronostic ?

If the septic arthritis is treated promptly, there is a good chance of complete cure with no long-term problems.

If there is delay in treatment, the infection can quickly destroy parts of the joint causing permanent damage. This may lead to long-term pain, reduced movement of the joint and some disability. In some cases the infection becomes severe and leads to blood poisoning (septicaemia). This is a serious complication which can be fatal but is now rare in the UK since antibiotic medicines became available.

How do I prevent septic arthritis?

While some risk factors cannot be controlled, there are steps you can take to reduce the chances of developing septic arthritis:

  • Promptly treat infections

    If you have an infection, particularly in the skin or bones, make sure to follow the treatment plan to prevent it spreading.

  • Good hygiene

    Regularly wash your hands and clean any cuts, wounds, or surgical sites to reduce the risk of infection.

  • Manage chronic conditions

    Conditions such as diabetes, rheumatoid arthritis, or immunosuppression require careful management to minimize the risk of infections.

Questions fréquemment posées

Puis-je avoir une arthrite septique plus d'une fois ?

L'article n'indique pas explicitement si l'arthrite septique peut réapparaître. Cependant, il mentionne que si vous avez certains types d'arthrite ou un système immunitaire affaibli, vous êtes à risque accru. Traiter rapidement les infections et gérer les maladies chroniques sont également soulignés comme des mesures préventives, ce qui pourrait suggérer une possibilité de récurrence si les facteurs de risque persistent ou si de nouvelles infections surviennent.

Quel type de dommages permanents l'arthrite septique peut-elle causer si elle n'est pas traitée rapidement ?

Si le traitement de l'arthrite septique est retardé, l'infection peut rapidement détruire des parties de l'articulation affectée. Cette destruction peut entraîner des douleurs à long terme, une réduction du mouvement de l'articulation et potentiellement un certain niveau d'incapacité permanente.

Combien de temps après l'apparition des symptômes dois-je commencer le traitement de l'arthrite septique ?

L'article indique que les antibiotiques sont commencés dès que possible. Il avertit également qu'un retard dans le traitement peut rapidement détruire des parties de l'articulation, causant des dommages permanents. Bien qu'il ne donne pas de délai précis, il souligne l'urgence d'un traitement rapide pour avoir une bonne chance de guérison complète et prévenir les problèmes à long terme.

Est-il courant que les personnes avec des articulations artificielles développent une arthrite septique ?

Bien que l'arthrite septique puisse affecter les personnes ayant des articulations de remplacement comme des hanches ou des genoux artificiels, l'article décrit l'infection pendant la chirurgie ou avec une prothèse articulaire comme une 'complication rare'. Cependant, avoir une prothèse articulaire est répertorié comme un facteur de risque, ce qui signifie que cela augmente votre susceptibilité par rapport à quelqu'un qui n'en a pas.

Combien de temps devrai-je prendre des antibiotiques pour une arthrite septique ?

Après des doses initiales élevées administrées par voie intraveineuse, vous devrez continuer à prendre des antibiotiques pendant plusieurs semaines. Ce traitement prolongé est important pour s'assurer que toute infection a été éliminée de l'articulation affectée.

Lectures complémentaires et références

  • Momodu II, Savaliya V; Arthrite septique. StatPearls, janvier 2025
  • Wall C, Donnan L; Arthrite septique chez les enfants. Aust Fam Physician. 2015 Avr;44(4):213-5.
  • Lamagni T; Épidémiologie et charge des infections des articulations prothétiques. J Antimicrob Chemother. 2014 Sep;69 Suppl 1:i5-10. doi: 10.1093/jac/dku247.
  • Gamalero L, Ferrara G, Giani T, et al; Arthrite aiguë chez les enfants : Comment discerner entre arthrite septique et non septique ? Children (Basel). 2021 Oct 13;8(10). pii: children8100912. doi: 10.3390/children8100912.
  • Wang J, Wang L; Nouvelles interventions thérapeutiques pour une meilleure gestion de l'arthrite septique. BMC Musculoskelet Disord. 2021 Jun 9;22(1):530. doi: 10.1186/s12891-021-04383-6.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

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Looking for more in-depth clinical detail? Our Professional Reference articles are written for doctors, nurses and other healthcare professionals. They include comprehensive clinical guidance, diagnostic information and UK/European evidence summaries. If you need the clinical version, you can read the Professional Reference article on this topic.

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