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Malabsorption gastro-intestinale

Gastrointestinal malabsorption syndrome means a failure to fully absorb digested foods from the gut (bowel) into your body. There are many different causes. Prolonged intestinal malabsorption may cause problems because of a lack of carbohydrates, proteins, fats, minerals and vitamins that are essential to keep you healthy.

The treatment will depend on the cause of malabsorption but will also include supplements and other ways to make up for the reduced amount of carbohydrate, protein, fat, minerals and vitamins getting into your gastrointestinal tract.

En un coup d'œil

  • Gastrointestinal malabsorption means your gut cannot absorb enough nutrients from food.

  • Symptoms include tiredness, weight loss, and persistent diarrhoea.

  • Stools may be pale, bulky, smelly, and difficult to flush.

  • It can cause deficiencies such as iron, folate, and vitamin B12 deficiency.

  • Common causes in the UK are coeliac disease, Crohn's disease, and chronic pancreatitis.

  • Diagnosis involves blood tests, stool tests, and sometimes imaging scans.

  • Treatment focuses on the underlying cause and nutritional support.

What are the symptoms of gastrointestinal malabsorption?

There may be no symptoms if the malabsorption is mild and has not continued for very long. More severe or persistent malabsorption may lead to:

Fatigue (épuisement)

This is because of a lack of energy as you are not absorbing nutrients and essential vitamins and minerals from food.

Perte de poids

If you can't absorb enough energy (calories) from your food then this will cause you to lose weight (and may cause poor growth in children).

Persistent (chronic) diarrhoea

This is a common symptom of persistent malabsorption.

Pale, bulky and smelly stools (steatorrhoea)

This is because there is excessive fat in the stools and they become pale, bulky and very smelly. Fatty stools float and are difficult to flush away. They often leave a greasy rim around the pan.

Intestinal malabsorption may also cause:

There may also be other symptoms due to the particular underlying condition that is causing the malabsorption.

What are the causes of gastrointestinal malabsorption?

The most common causes in the UK are maladie cœliaque, maladie de Crohn and chronic pancreatitis. However, the malabsorption of simple carbohydrates affects about 1 in 4 people in Europe. Some diseases associated with malabsorption are found more often in some families - for example, coeliac disease, Crohn's disease, la fibrose kystique and lactose intolerance.

The causes of gastrointestinal malabsorption include:

Problems with absorbing food from the gut (bowel) into your body

Structural causes

Malabsorption may be cause by loss of part of the bowel that is essential to absorb the broken down (digested) food into the body - for example:

  • Removal of the stomach or part of the bowel after a stomach or bowel operation.

  • maladie de Crohn.

Causes outside the bowel

Examples include:

What tests are needed?

Initial tests will include analyses de sang et stool tests. Further tests may include an abdominal échographie, barium studies and a tomodensitométrie (TDM) ou un imagerie par résonance magnétique (IRM). Any further tests will depend on the likely underlying cause of the intestinal malabsorption.

What are the treatments for gastrointestinal malabsorption?

The treatment will mainly depend on the underlying cause of the malabsorption. However, treatment will also be needed to increase the amount of essential nutrients in the body, including carbohydrates, proteins, fats, minerals and fat-soluble vitamins (nutritional support).

Questions fréquemment posées

Can malabsorption be cured?

The treatment for malabsorption primarily focuses on addressing the underlying condition causing it. Therefore, whether it can be 'cured' depends on the specific cause. Additionally, part of the treatment involves ensuring the body receives essential nutrients like carbohydrates, proteins, fats, minerals, and fat-soluble vitamins through nutritional support.

What happens if fat is not absorbed properly?

If fat is not absorbed properly, it can lead to pale, bulky, and very smelly stools. These stools, known as steatorrhoea, contain excessive fat, often float, are difficult to flush, and can leave a greasy rim around the toilet pan.

Are there any health complications from long-term malabsorption?

Yes, long-term malabsorption can lead to several complications due to insufficient nutrient absorption. These include iron deficiency, iron-deficiency anaemia, folate deficiency, vitamin B12 deficiency, abnormal bleeding due to low vitamin K, and vitamin D deficiency, which can manifest as rickets or osteomalacia. Oedema can also occur because of insufficient protein and calories absorbed into the body.

Can malabsorption be caused by lifestyle factors like eating disorders?

Yes, malabsorption can be influenced by factors outside the bowel, including eating disorders such as anorexia nervosa and bulimia nervosa. An overactive thyroid gland (hyperthyroidism) can also be a cause.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Dr Colin Tidy, MRCGP

Médecin généraliste, Auteur médical

MBBS, MRCGP, MRCP (Paediatrics), DCH

Le Dr Colin Tidy est un médecin du NHS, basé dans l'Oxfordshire.

À propos du critiqueVoir la biographie complète

Image de l'auteur

Dr Colin Tidy, MRCGP

Médecin généraliste, Auteur médical

MBBS, MRCGP, MRCP (Paediatrics), DCH

Le Dr Colin Tidy est un médecin du NHS, basé dans l'Oxfordshire.

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